England’s Jonathan Trott has left the Ashes tour of Australia because of a long-standing stress-related condition.
Batsman Trott scored 19 runs in two innings during England’s first Test defeat and struggled against the bowling of Mitchell Johnson.
“I don’t think it is right that I’m playing knowing that I’m not 100%,” said the 32-year-old.
England coach Andy Flower added: “He needs time away from this environment and time with his family.”
The tourists will play an Australian Chairman’s XI over two days from Friday, before the second Test in Adelaide on 5 December.
Trott scored 10 and 9 in two innings as England suffered a 381-run defeat in the first Test at the Gabba in Brisbane.
“I cannot currently operate at the level I have done in the past,” he added.
“My priority now is to take a break from cricket so that I can focus on my recovery.”
The displays of England’s batsmen were branded “poor and weak” by Australia’s David Warner after the opening Test.
England captain Alastair Cook labelled the comments “disrespectful,” a view shared by Flower who says Warner’s views had no impact on Trott’s decision to leave.
“Jonathan has been struggling with this condition for quite a while,” added Flower.
“We have been on tour for about a month and he has had his ups and downs through that month and it is not directly related to that.
“I would also say players commenting to fellow professionals in the media is disrespectful and I think on this occasion he [Warner] has got that horribly wrong.”
Flower is hopeful Warwickshire’s Trott will return to the international setup in the future, but England have decided not to immediately summon a replacement for the tour.
Ian Bell could move up the order to number three, while the spare middle-order spot will be filled by Jonny Bairstow, the uncapped Gary Ballance, or all-rounder Ben Stokes, who would offer an extra bowling option.
Trott, who was named ICC and ECB Cricketer of the Year in 2011, is the third England cricketer to depart a tour with a stress-related illness in recent years.
Former opening batsman Marcus Trescothick left the 2005-06 India tour and the 2006-07 Ashes tour of Australia, while left-arm spinner Michael Yardy flew home from the 2011 World Cup.
Trescothick told BBC Radio 5 live: “It would have been a horrible decision to make, to come out and talk about these things for the first time is tough, I’m sure he’s not feeling great at all, but he’s definitely made the right decision.
“When you’re in that state of mind you get very good at hiding these things but there comes a time where you have to talk about it. It just gets too big sometimes and the best thing to do is to take some time away from it.
“It’s debilitating, it grinds you down, and its difficult to escape from, you can’t get away from it in all areas of your life. There is no hiding place from it, 24/7. It’s really really tough and it will take time for him to get back on track again.”